Basics of Genetics

Course Title: Basics of Genetics

Course Code: MS 203

Semester: Second

 Credit Hours: 2 Hours (2 + 0) (2 Weeks)

Requirements: Biochemistry

Introduction and Justification:

All human beings are equal and, at the same time, are different. They carry the same genetic information, except for tiny differences where we differ in our personality, appearance, behavior, and health conditions. During the past few years, our knowledge about the genetic basis of health status changed rapidly after the completion of the study of the human genome and clarification of the full genetic information consisting of three billion bases for encoding the scheme of human life. Physicians, in this era of molecular medicine, have to know the basics of human genetics by which they can provide genetic information that will help in determining health and disease. The human genome contains about 20,600 gene-encoded protein, The search for the differences and genetic variants among a group of people or individuals may explain the relationship between genotype and phenotype; genes interact with each other, as well as genes and environment interacting, to investigate the role of mutations and the formation of tumors and to assist in diagnosis before delivery and the manner of gene therapy in the medical fields.

 Objectives of the course

 Overall objective:

Study basics of genetics

Specific objectives

By the end of this course, the student should be able to:

Describe the basic concepts and principles of genetic

 Explain how genetic information is passed between generations

Recognize the role of genetic information in determining the characteristics of individuals

Describe the interaction between genes and the environment

Discusses the role of genetics in causing the disease

. Defines the basic concepts of recombinant DNA technology and genetic engineering

Methods of students assessment:

 Attendances and performances     10%

 Practical Objective Structural 20%

 Multiple-Choice Questions           40%

 Essays and Short Questions        30%

References:

12.1 Online Mendelian Inheritance in Man, National Centre for Biotechnology Information http://www.ncbi.nlm.nih.gov/omim).

12.2 HUMAN GENETICS: CONCEPTS AND APPLICATIONS, EIGHTH EDITION (2008).RICKI LEWIS. The McGraw-Hill COMPANIES, Inc.

12.3 HUMAN GENETICS: FROM MOLECULES TO MEDICINE, FIRST EDITION (2012).CHRISTIAN PATRICK SCHAAF, JOHANNES ZSCHOCKE, & LORRAINE POTOCK.LIPPINCOTT WILLIAMS & WILKINS, A WOLTERS KLUWER BUSINESS.

12.4 CONCEPTS OF GENETICS, FIRST EDITION (2012).ROBERT J. BROOKER.THE MCGRAW-HILL COMPANIES, Inc.

12.5 GENETICS: A CONCEPTUAL APPROACH, FOURTH EDITION (2012).BENJAMIN A. PIERCE.W. H. FREEMAN AND COMPANY, New York.

12.6 GENETICS (NATIONAL MEDICAL SERIES FOR INDEPENDENT STUDY), SECOND EDITION (1996).FRED J. DILL, MICAHEL R. HAYDEN, BARBARA C. MCGILLIVRAY, JM FRIEDMAN.WILLIAMS & WILKINS A WAVERLY COMPANY